David Lake

Exobiologist and one of the world's foremost authorities on malectoplasm, the substance from which Ghouls are formed. A child prodigy, Lake had his science doctorate by the age of 21. He was undergoing astronaut training at the time of the Infestation. Having lost his brother in one of the early Ghoul attacks (at which time he was almost killed himself), Lake devoted the next years of his life learning all he could about the malicious substance that was threatening the globe. He was the first to realize that Ghouls had weak spots that could be exploited, and also was the first to document the mimicking properties of malectoplasm. Lake works virtually alone in the ADEF malectoplasm labs, although he remains in close contact with other researchers around the globe. Single, Lake lives at the ADEF complex with his dog, Hippie.

Pamela Gray

Chemist and co-creator of Ghoo, the only substance known to have a harmful effect on Ghouls. As a girl, she idolized her mother Paula, and upon earning her doctorate in chemistry joined her as a developmental chemist for a major household products company. Like David Lake, she lost family members -- her father and two sisters -- soon after the original Infestation. She and her mother soon became obsessed with finding a chemical method of stopping the Ghouls, and eventually created Ghoo. Not long after that, however, Paula Gray was killed in a mysterious Ghoul attack. Since then Gray has worked in the ADEF chemical labs in an attempt to perfect a form of Ghoo that will work regardless of where it strikes the Ghoul. She is also single, and longs for the day when she can leave the ADEF complex and return to her family home.

Cornealius

Freelance Ghoul hunter. Exterminator for hire. A former Special Forces officer, he was one of the original members of ADEF, and perfected the techniques for the successful hunting and extermination of Ghouls. When he left ADEF, it was assumed by many, including Gen. Zone (below) that Cornealius had only profit as a motive, but on many an occasion has proved that theory wrong. The real motives for his lone wolf status are known only by the hunter himself. Very little personal information is known about Cornealius. He has revealed his first name only to a select few, including Gray.

Gen. James Harold Zone

Has been the leader of ADEF -- the Aberration Deterrent and Eradication Forces -- from its inception. Like the others, Zone, too, has lost family members to Ghouls. In his case, it was his young son, John. His obsession with wiping out the Ghouls has made him determined to have the top scientific minds in the world working for ADEF, which is why he keeps Lake and Gray virtually under house arrest. As Cornealius' former commanding officer, he has great respect for the hunter's abilities, but was angered that he chose to leave ADEF. Barely tolerates the hunter's presence in the ADEF complex.

Heston Oliver Wynn

Evil multi-billionaire. Former computer nerd who launched an empire based on his many creations. Sees the Ghoul infestation as an opportunity to tighten his ever-widening grip on the Earth. Is attempting, like Pamela Gray, to perfect a Ghoo that needs no weak spot, and will go to any lengths to stop scientists who are competing with him.